Bifonazole vs Other Azoles

Fungal skin infections like athlete’s foot, ringworm, or jock itch can be irritating and painful. But you don’t need to keep suffering! You need a good antifungal cream that you can apply easily, is effective, and is an anti-inflammatory without steroid– like Canespro® Once-Daily by Canesten.

Benefits of Canespro® Once-Daily by Canesten

The active ingredient in Canespro® Once-Daily is bifonazole, which belongs to a group of medicines called Azoles.

Azoles are used to restrict the growth of various fungi that can cause health issues in people. Other common Azole antifungals are fluconazole, itraconazole, clotrimazole, and ketoconazole.1

However, bifonazole cream may have a few added benefits, including its ability to eliminate a wide range of fungi and moulds. These include dermatophytes and dimorphic fungi, as well as some gram-positive bacteria (Corynebacterium minutissimum).2

Canespro® Once-Daily by Canesten is a good choice for those with fungal skin problems because in addition to being effective, it does not contain steroids, has anti-inflammatory properties, and is easy to use. It also has minimal side effects. Jock itch, athlete’s foot, and ringworm are just some of the fungal irritations Canespro® Once-Daily can help treat.3

How does Canespro® Once-Daily compare to other antifungal treatments?

Here is how Canespro® Once-Daily compares to other azoles, according to studies2, 4:

  • How long does this antifungal cream take to work? Different fungal infections have different durations of treatment. However, bifonazole needs to be applied only once a day throughout the length of treatment. Because of this, Canespro® Once-Daily by Canesten is more convenient to use for those with fungal skin conditions.
  • This helps to improve compliance to treatment, and results in better healing, and prevention of recurrence. Many other antifungal ointments have to be applied twice a day, possibly making them inconvenient to use and making people less likely to use them as directed.
  • Like other imidazole antifungal treatments such as clotrimazole, ketoconazole, miconazole and others, Canespro® Once-Daily is effective against yeast and dermatophytes. These cause common fungal irritations like candidiasis, and tinea.
  • Canespro® Once-Daily works better at inhibiting some strains of dermatophytes and Candida, compared to clotrimazole, as shown in vitro studies5, 6.

  • Canespro® Once-Daily is effective at treating infections caused by dermatophytes. It has a high capacity for skin penetration at high concentration levels, which in turn enables it to inhibit the activity of dermatophytes found even in deeper skin layers.

Consult your doctor

You should never self-diagnose and self-medicate for what you think might be a yeast or fungal infection. This is because their symptoms can be similar to other skin infections. Seek a doctor’s advice for the best way to treat fungal infections.

A medical professional’s advice is also essential before using bifonazole cream on a baby, if you are pregnant or breastfeeding, or you’re already on medications for your skin condition.

Canespro® Once-Daily should not be used if you are allergic to bifonazole or the medication has expired. It should never be applied to areas of the body that have mucosal membranes, like the vagina, eyes and mouth.

Seek medical advice without delay if Canespro® Once-Daily is swallowed. You should also always follow the instructions on the packaging for best results.


  1. Azole Antifungals. Retrieved on February 8, 2022 from
  2. Bifonazole. A review of its antimicrobial activity and therapeutic use in superficial mycoses. Lackner, T.E. and Clissold, S.P. Drug Evaluation. 2012. Retrieved on February 8, 2022 from
  3. Canesten Once Daily Bifonazole Topical Cream. NPS MedicineWise. 2022. Retrieved on February 8, 2022 from
  4. In vitro studies of a new imidazole antimycotic, bifonazole, in comparison with clotrimazole and miconazole. Arzneimittel-forschung. 1983. Retrieved on February 02, 2022 from
  5. Clin Dermatol Rev 2017; 1: S24-9.
  6. Am Fam Physician. 2002; 65: 2095-2103.